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miR-503/Apelin-12 mediates high glucose-induced microvascular endothelial cells injury via JNK and p38MAPK signaling pathway

INTRODUCTION: Diabetic patients are often accompanied by complications of diabetic vascular disease, which could lead to heart failure or stroke. In this work, we explored the role of miR-503/Apelin-12 in diabetic angiopathy (DA) in vitro. METHODS: ELISA and qPCR were applied to assess the expressio...

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Detalles Bibliográficos
Autores principales: Chen, Kai, Zhao, Xin-Lan, Li, Lang-Bo, Huang, Ling-Yun, Tang, Zhuo, Luo, Juan, Yang, Li, Qin, Ai-Ping, Hu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970136/
https://www.ncbi.nlm.nih.gov/pubmed/31989001
http://dx.doi.org/10.1016/j.reth.2019.12.002