Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway

CONTEXT: Cisplatin-based chemotherapy was widely used in treating human malignancies. However, side effects and chemoresistance remains the major obstacle. OBJECTIVE: To verify whether natural borneol (NB) can enhance cisplatin-induced glioma cell apoptosis and explore the mechanism. MATERIALS AND M...

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Detalles Bibliográficos
Autores principales: Cao, Wen-qiang, Zhai, Xiao-qian, Ma, Ji-wei, Fu, Xue-qi, Zhao, Bai-song, Zhang, Pu, Fu, Xiao-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970185/
https://www.ncbi.nlm.nih.gov/pubmed/31875760
http://dx.doi.org/10.1080/13880209.2019.1703756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970185/
https://www.ncbi.nlm.nih.gov/pubmed/31875760
http://dx.doi.org/10.1080/13880209.2019.1703756

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