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Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway
CONTEXT: Cisplatin-based chemotherapy was widely used in treating human malignancies. However, side effects and chemoresistance remains the major obstacle. OBJECTIVE: To verify whether natural borneol (NB) can enhance cisplatin-induced glioma cell apoptosis and explore the mechanism. MATERIALS AND M...
Autores principales: | Cao, Wen-qiang, Zhai, Xiao-qian, Ma, Ji-wei, Fu, Xue-qi, Zhao, Bai-song, Zhang, Pu, Fu, Xiao-yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970185/ https://www.ncbi.nlm.nih.gov/pubmed/31875760 http://dx.doi.org/10.1080/13880209.2019.1703756 |
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