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Inhibitory Effects of Columbianadin on Nociceptive Behaviors in a Neuropathic Pain Model, and on Voltage-Gated Calcium Currents in Dorsal Root Ganglion Neurons in Mice

Radix angelicae pubescentis (RAP) has been used in Chinese traditional medicine to treat painful diseases such as rheumatism and headache. A previous study has reported that columbianadin (CBN), a major coumarin in RAP inhibits acute and inflammatory pain behaviors. However, the effects of CBN on ne...

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Detalles Bibliográficos
Autores principales: Su, Xiaolin, Wu, Bin, Zhang, Wentong, Ji, Yong-Hua, Wang, Qiuhong, Tan, Zhi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970200/
https://www.ncbi.nlm.nih.gov/pubmed/31998126
http://dx.doi.org/10.3389/fphar.2019.01522