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Inhibitory Effects of Columbianadin on Nociceptive Behaviors in a Neuropathic Pain Model, and on Voltage-Gated Calcium Currents in Dorsal Root Ganglion Neurons in Mice
Radix angelicae pubescentis (RAP) has been used in Chinese traditional medicine to treat painful diseases such as rheumatism and headache. A previous study has reported that columbianadin (CBN), a major coumarin in RAP inhibits acute and inflammatory pain behaviors. However, the effects of CBN on ne...
Autores principales: | Su, Xiaolin, Wu, Bin, Zhang, Wentong, Ji, Yong-Hua, Wang, Qiuhong, Tan, Zhi-Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970200/ https://www.ncbi.nlm.nih.gov/pubmed/31998126 http://dx.doi.org/10.3389/fphar.2019.01522 |
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