Cargando…

Edaravone Ameliorates Renal Warm Ischemia-Reperfusion Injury by Downregulating Endoplasmic Reticulum Stress in a Rat Resuscitation Model

BACKGROUND: This study was conducted to explore whether the effect of edaravone (5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol3-one, EDR) can ameliorate renal warm ischemia-reperfusion injury (IRI) by modulating endoplasmic reticulum stress (ERS) and its downstream effector after cardiac arrest (CA) and...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Zhao-Yin, Wu, Zhi-Jiang, Zheng, Jun-Hui, Li, Nuo, Lu, Jun-Yu, Chen, Meng-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970244/
https://www.ncbi.nlm.nih.gov/pubmed/32021102
http://dx.doi.org/10.2147/DDDT.S211906