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Edaravone Ameliorates Renal Warm Ischemia-Reperfusion Injury by Downregulating Endoplasmic Reticulum Stress in a Rat Resuscitation Model
BACKGROUND: This study was conducted to explore whether the effect of edaravone (5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol3-one, EDR) can ameliorate renal warm ischemia-reperfusion injury (IRI) by modulating endoplasmic reticulum stress (ERS) and its downstream effector after cardiac arrest (CA) and...
Autores principales: | Fu, Zhao-Yin, Wu, Zhi-Jiang, Zheng, Jun-Hui, Li, Nuo, Lu, Jun-Yu, Chen, Meng-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970244/ https://www.ncbi.nlm.nih.gov/pubmed/32021102 http://dx.doi.org/10.2147/DDDT.S211906 |
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