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FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway

PURPOSE: Fanconi anemia complementation group I (FANCI) is a key protein in ribosome biogenesis and DNA repair. Here, we aimed to determine the clinical significance, prognostic value and biology functions of FANCI in lung adenocarcinoma (LUAD). METHODS: The expression of FANCI in LUAD tissue and it...

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Detalles Bibliográficos
Autores principales: Zheng, Pengchao, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970268/
https://www.ncbi.nlm.nih.gov/pubmed/32021289
http://dx.doi.org/10.2147/OTT.S230333