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The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis

BACKGROUND: Isatin derivatives have extensive biological activities, such as antitumor. IF203, a novel isatin derivative, has not previously been reported to have antitumor activity. METHODS: Acid phosphatase assays (APAs) and Ki-67 immunohistochemistry were used to detect the proliferation of HepG2...

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Detalles Bibliográficos
Autores principales: Shang, Yinghui, Wang, Qinghai, Li, Jian, Zhao, Qiangqiang, Huang, Xueyuan, Dong, Hang, Liu, Haiting, Zhang, Ye, Zhang, Junhua, Gui, Rong, Nie, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970269/
https://www.ncbi.nlm.nih.gov/pubmed/32021291
http://dx.doi.org/10.2147/OTT.S232594