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Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells

PURPOSE: Breast cancer is the most common malignancy among women across the globe. Despite concerted efforts to improve the prevailing treatment modalities, the overall prognosis of breast cancer remains unsatisfactory. Recently, antiproliferative activity of Brevilin A (Brv-A), a sesquiterpene lact...

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Detalles Bibliográficos
Autores principales: Saleem, Muhammad Zubair, Nisar, Muhammad Azhar, Alshwmi, Mohammed, Din, Syed Riaz Ud, Gamallat, Yaser, Khan, Muhammad, Ma, Tonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970270/
https://www.ncbi.nlm.nih.gov/pubmed/32021288
http://dx.doi.org/10.2147/OTT.S228702