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Hair follicle stem cells regulate retinoid metabolism to maintain the self-renewal niche for melanocyte stem cells

Metabolites are major biological parameters sensed by many cell types in vivo, whether they function as signaling mediators of SC and niche cross talk to regulate tissue regeneration is largely unknown. We show here that deletion of the Notch pathway co-factor RBP-J specifically in mouse HFSCs trigg...

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Detalles Bibliográficos
Autores principales: Lu, Zhiwei, Xie, Yuhua, Huang, Huanwei, Jiang, Kaiju, Zhou, Bin, Wang, Fengchao, Chen, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970533/
https://www.ncbi.nlm.nih.gov/pubmed/31898934
http://dx.doi.org/10.7554/eLife.52712