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Inflammation-Associated Microsatellite Alterations Caused by MSH3 Dysfunction Are Prevalent in Ulcerative Colitis and Increase With Neoplastic Advancement

OBJECTIVES: Inflammation-associated microsatellite alterations (also known as elevated microsatellite alterations at selected tetranucleotide repeats [EMAST]) result from IL-6–induced nuclear-to-cytosolic displacement of the DNA mismatch repair (MMR) protein MSH3, allowing frameshifts of dinucleotid...

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Detalles Bibliográficos
Autores principales:	Munakata, Koji, Koi, Minoru, Kitajima, Takahito, Tseng-Rogenski, Stephanie, Uemura, Mamoru, Matsuno, Hiroshi, Kawai, Kenji, Sekido, Yuki, Mizushima, Tsunekazu, Toiyama, Yuji, Yamada, Takuya, Mano, Masayuki, Mita, Eiji, Kusunoki, Masato, Mori, Masaki, Carethers, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970556/ https://www.ncbi.nlm.nih.gov/pubmed/31789935 http://dx.doi.org/10.14309/ctg.0000000000000105

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