Cargando…
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation
Antibody combinations targeting cell surface receptors are a new modality of cancer therapy. The trafficking and signalling mechanisms regulated by such therapeutics are not fully understood but could underlie differential tumour responses. We explored EGFR trafficking upon treatment with the antibo...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970994/ https://www.ncbi.nlm.nih.gov/pubmed/31959764 http://dx.doi.org/10.1038/s41598-019-57153-9 |