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Improved multiparametric scrape loading-dye transfer assay for a simultaneous high-throughput analysis of gap junctional intercellular communication, cell density and viability

Gap junctional intercellular communication (GJIC) is a vital cellular process required for maintenance of tissue homeostasis. In vitro assessment of GJIC represents valuable phenotypic endpoint that could be effectively utilized as an integral component in modern toxicity testing, drug screening or...

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Detalles Bibliográficos
Autores principales: Dydowiczová, Aneta, Brózman, Ondřej, Babica, Pavel, Sovadinová, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971000/
https://www.ncbi.nlm.nih.gov/pubmed/31959888
http://dx.doi.org/10.1038/s41598-020-57536-3