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Improved multiparametric scrape loading-dye transfer assay for a simultaneous high-throughput analysis of gap junctional intercellular communication, cell density and viability
Gap junctional intercellular communication (GJIC) is a vital cellular process required for maintenance of tissue homeostasis. In vitro assessment of GJIC represents valuable phenotypic endpoint that could be effectively utilized as an integral component in modern toxicity testing, drug screening or...
Autores principales: | Dydowiczová, Aneta, Brózman, Ondřej, Babica, Pavel, Sovadinová, Iva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971000/ https://www.ncbi.nlm.nih.gov/pubmed/31959888 http://dx.doi.org/10.1038/s41598-020-57536-3 |
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