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Delineation of hypoxia-induced proteome shifts in osteosarcoma cells with different metastatic propensities

Osteosarcoma (OS) is the most common bone cancer in children and young adults. Solid tumors are characterized by intratumoral hypoxia, and hypoxic cells are associated with the transformation to aggressive phenotype and metastasis. The proteome needed to support an aggressive osteosarcoma cell pheno...

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Detalles Bibliográficos
Autores principales: Song, Zifeng, Pearce, Martin C., Jiang, Yuan, Yang, Liping, Goodall, Cheri, Miranda, Cristobal L., Milovancev, Milan, Bracha, Shay, Kolluri, Siva K., Maier, Claudia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971036/
https://www.ncbi.nlm.nih.gov/pubmed/31959767
http://dx.doi.org/10.1038/s41598-019-56878-x