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Delineation of hypoxia-induced proteome shifts in osteosarcoma cells with different metastatic propensities
Osteosarcoma (OS) is the most common bone cancer in children and young adults. Solid tumors are characterized by intratumoral hypoxia, and hypoxic cells are associated with the transformation to aggressive phenotype and metastasis. The proteome needed to support an aggressive osteosarcoma cell pheno...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971036/ https://www.ncbi.nlm.nih.gov/pubmed/31959767 http://dx.doi.org/10.1038/s41598-019-56878-x |