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Linezolid and Rifampicin Combination to Combat cfr-Positive Multidrug-Resistant MRSA in Murine Models of Bacteremia and Skin and Skin Structure Infection

Linezolid resistance mediated by the cfr gene in MRSA represents a global concern. We investigated relevant phenotype differences between cfr-positive and -negative MRSA that contribute to pathogenesis, and the efficacy of linezolid-based combination therapies in murine models of bacteremia and skin...

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Detalles Bibliográficos
Autores principales: Zhou, Yu-Feng, Li, Liang, Tao, Meng-Ting, Sun, Jian, Liao, Xiao-Ping, Liu, Ya-Hong, Xiong, Yan Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971047/
https://www.ncbi.nlm.nih.gov/pubmed/31993042
http://dx.doi.org/10.3389/fmicb.2019.03080