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Linezolid and Rifampicin Combination to Combat cfr-Positive Multidrug-Resistant MRSA in Murine Models of Bacteremia and Skin and Skin Structure Infection
Linezolid resistance mediated by the cfr gene in MRSA represents a global concern. We investigated relevant phenotype differences between cfr-positive and -negative MRSA that contribute to pathogenesis, and the efficacy of linezolid-based combination therapies in murine models of bacteremia and skin...
Autores principales: | Zhou, Yu-Feng, Li, Liang, Tao, Meng-Ting, Sun, Jian, Liao, Xiao-Ping, Liu, Ya-Hong, Xiong, Yan Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971047/ https://www.ncbi.nlm.nih.gov/pubmed/31993042 http://dx.doi.org/10.3389/fmicb.2019.03080 |
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