Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro

Molecular chaperones play important roles in preventing protein misfolding and its potentially harmful consequences. Deterioration of molecular chaperone systems upon ageing are thought to underlie age-related neurodegenerative diseases, and augmenting their activities could have therapeutic potenti...

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Detalles Bibliográficos
Autores principales: Chen, Gefei, Andrade-Talavera, Yuniesky, Tambaro, Simone, Leppert, Axel, Nilsson, Harriet E., Zhong, Xueying, Landreh, Michael, Nilsson, Per, Hebert, Hans, Biverstål, Henrik, Fisahn, André, Abelein, Axel, Johansson, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971075/
https://www.ncbi.nlm.nih.gov/pubmed/31959875
http://dx.doi.org/10.1038/s42003-020-0757-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971075/
https://www.ncbi.nlm.nih.gov/pubmed/31959875
http://dx.doi.org/10.1038/s42003-020-0757-z

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