Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells

Lactate is a ubiquitous molecule in cancer. In this exploratory study, our aim was to test the hypothesis that lactate could function as an oncometabolite by evaluating whether lactate exposure modifies the expression of oncogenes, or genes encoding transcription factors, cell division, and cell pro...

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Detalles Bibliográficos
Autores principales: San-Millán, Iñigo, Julian, Colleen G., Matarazzo, Christopher, Martinez, Janel, Brooks, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971189/
https://www.ncbi.nlm.nih.gov/pubmed/32010625
http://dx.doi.org/10.3389/fonc.2019.01536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971189/
https://www.ncbi.nlm.nih.gov/pubmed/32010625
http://dx.doi.org/10.3389/fonc.2019.01536

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