Biodistribution and imaging of an hsp90 ligand labelled with (111)In and (67)Ga for imaging of cell death

BACKGROUND: 4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid (GSAO) when conjugated at the γ-glutamyl residue with fluorophores and radio-isotopes is able to image dead and dying cells in vitro and in vivo by binding to intracellular 90-kDa heat shock proteins (hsp90) when cell membrane integri...

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Detalles Bibliográficos
Autores principales: Ho Shon, Ivan, Kumar, Divesh, Sathiakumar, Chithradevi, Berghofer, Paula, Van, Khang, Chicco, Andrew, Hogg, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971215/
https://www.ncbi.nlm.nih.gov/pubmed/31960173
http://dx.doi.org/10.1186/s13550-020-0590-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971215/
https://www.ncbi.nlm.nih.gov/pubmed/31960173
http://dx.doi.org/10.1186/s13550-020-0590-x

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