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Hypermethylation of mitochondrial DNA in vascular smooth muscle cells impairs cell contractility
Vascular smooth muscle cell (SMC) from arterial stenotic-occlusive diseases is featured with deficiency in mitochondrial respiration and loss of cell contractility. However, the regulatory mechanism of mitochondrial genes and mitochondrial energy metabolism in SMC remains elusive. Here, we described...
Autores principales: | Liu, Yue-Feng, Zhu, Juan-Juan, Yu Tian, Xiao, Liu, Han, Zhang, Tao, Zhang, Yun-Peng, Xie, Si-An, Zheng, Ming, Kong, Wei, Yao, Wei-Juan, Pang, Wei, Zhao, Chuan-Rong, Tang, Yuan-Jun, Zhou, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971246/ https://www.ncbi.nlm.nih.gov/pubmed/31959742 http://dx.doi.org/10.1038/s41419-020-2240-7 |
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