Cargando…
Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes
Obesity, caused by the dysfunction of white adipose tissue (WAT), is reportedly accompanied by exacerbation of lipolysis. Perilipin 1 (PLIN1), which forms a coat around lipid droplets, interacts with several lipolysis proteins to regulate lipolysis. While it is known that perilipin family proteins a...
Autores principales: | Mizunoe, Yuhei, Kobayashi, Masaki, Hoshino, Shunsuke, Tagawa, Ryoma, Itagawa, Rei, Hoshino, Ayana, Okita, Naoyuki, Sudo, Yuka, Nakagawa, Yoshimi, Shimano, Hitoshi, Higami, Yoshikazu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971249/ https://www.ncbi.nlm.nih.gov/pubmed/31959889 http://dx.doi.org/10.1038/s41598-020-57428-6 |
Ejemplares similares
-
Association between Lysosomal Dysfunction and Obesity-Related Pathology: A Key Knowledge to Prevent Metabolic Syndrome
por: Mizunoe, Yuhei, et al.
Publicado: (2019) -
Srebp-1c/Fgf21/Pgc-1α Axis Regulated by Leptin Signaling in Adipocytes—Possible Mechanism of Caloric Restriction-Associated Metabolic Remodeling of White Adipose Tissue
por: Kobayashi, Masaki, et al.
Publicado: (2020) -
WWP1 knockout in mice exacerbates obesity‐related phenotypes in white adipose tissue but improves whole‐body glucose metabolism
por: Hoshino, Shunsuke, et al.
Publicado: (2020) -
Long-Term Dietary Taurine Lowers Plasma Levels of Cholesterol and Bile Acids
por: Tagawa, Ryoma, et al.
Publicado: (2022) -
Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways
por: Mizunoe, Yuhei, et al.
Publicado: (2017)