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STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts

Induction of autophagy can have beneficial effects in several human diseases, e.g. cancer and neurodegenerative diseases (ND). Here, we therefore evaluated the potential of two novel autophagy-inducing compounds, i.e. STF-62247 and pimozide, to stimulate autophagy as well as autophagic cell death (A...

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Detalles Bibliográficos
Autores principales: Kinzler, Maximilian N., Zielke, Svenja, Kardo, Simon, Meyer, Nina, Kögel, Donat, van Wijk, Sjoerd J. L., Fulda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971264/
https://www.ncbi.nlm.nih.gov/pubmed/31959760
http://dx.doi.org/10.1038/s41598-019-56990-y