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Multiscale bone quality analysis in osteoarthritic knee joints reveal a role of the mechanosensory osteocyte network in osteophytes

Osteophytes - bony outgrowths on joint structures - are found in healthy individuals but are specifically present in late osteoarthritis (OA). Osteophyte development and function is not well understood, yet biomechanical stimuli are thought to be critical. Bone adapts to mechanical forces via the ce...

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Detalles Bibliográficos
Autores principales: Rabelo, Gustavo Davi, vom Scheidt, Annika, Klebig, Felix, Hemmatian, Haniyeh, Citak, Mustafa, Amling, Michael, Busse, Björn, Jähn, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971279/
https://www.ncbi.nlm.nih.gov/pubmed/31959806
http://dx.doi.org/10.1038/s41598-019-57303-z