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Defining lncRNAs Correlated with CHO Cell Growth and IgG Productivity by RNA-Seq
How the long non-coding RNA (lncRNA) genome in recombinant protein producing Chinese hamster ovary (CHO) cell lines relates to phenotype is not well described. We therefore defined the CHO cell lncRNA transcriptome from cells grown in controlled miniature bioreactors under fed-batch conditions using...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971398/ https://www.ncbi.nlm.nih.gov/pubmed/31962234 http://dx.doi.org/10.1016/j.isci.2019.100785 |