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Exposure to 3-Nitropropionic Acid Mitochondrial Toxin Induces Tau Pathology in Tangle-Mouse Model and in Wild Type-Mice

Oxidative stress, particularly of mitochondrial origin, plays an important role in the pathogenesis of neurodegenerative disorders, including Alzheimer’s disease (AD) and other tauopathies. Controversies regarding the responses of tau phosphorylation state to various stimuli causing oxidative stress...

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Detalles Bibliográficos
Autores principales: Lahiani-Cohen, Inbal, Touloumi, Olga, Lagoudaki, Roza, Grigoriadis, Nikolaos, Rosenmann, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971403/
https://www.ncbi.nlm.nih.gov/pubmed/32010684
http://dx.doi.org/10.3389/fcell.2019.00321