Intrauterine exposure to chronic hypoxia in the rat leads to progressive diastolic function and increased aortic stiffness from early postnatal developmental stages

AIM: We sought to explore whether fetal hypoxia exposure, an insult of placental insufficiency, is associated with left ventricular dysfunction and increased aortic stiffness at early postnatal ages. METHODS: Pregnant Sprague Dawley rats were exposed to hypoxic conditions (11.5% FiO(2)) from embryon...

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Detalles Bibliográficos
Autores principales: Kumar, Praveen, Morton, Jude S., Shah, Amin, Do, Victor, Sergi, Consolato, Serrano‐Lomelin, Jesus, Davidge, Sandra T., Beker, Donna, Levasseur, Jody, Hornberger, Lisa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971413/
https://www.ncbi.nlm.nih.gov/pubmed/31960611
http://dx.doi.org/10.14814/phy2.14327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971413/
https://www.ncbi.nlm.nih.gov/pubmed/31960611
http://dx.doi.org/10.14814/phy2.14327

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