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Recruitment and Activation of the ULK1/Atg1 Kinase Complex in Selective Autophagy

Autophagy is a major cellular degradation pathway, which mediates the delivery of cytoplasmic cargo material into lysosomes. This is achieved by the specific sequestration of the cargo within double-membrane vesicles, the autophagosomes, which form de novo around this material. Autophagosome formati...

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Detalles Bibliográficos
Autores principales: Turco, Eleonora, Fracchiolla, Dorotea, Martens, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971721/
https://www.ncbi.nlm.nih.gov/pubmed/31351898
http://dx.doi.org/10.1016/j.jmb.2019.07.027