Abnormalities of DYRK1A-Cytoskeleton Complexes in the Blood Cells as Potential Biomarkers of Alzheimer’s Disease

BACKGROUND: DYRK1A is implicated in mental retardation and Alzheimer’s disease (AD) dementia of Down syndrome (DS) individuals. The protein is associated with cytoskeleton and altered expression has been shown to impair the cytoskeletal network via dosage effect. OBJECTIVE: Our original observations...

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Detalles Bibliográficos
Autores principales: Dowjat, Karol, Adayev, Tatyana, Wojda, Urszula, Brzozowska, Katarzyna, Barczak, Anna, Gabryelewicz, Tomasz, Hwang, Yu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971831/
https://www.ncbi.nlm.nih.gov/pubmed/31683476
http://dx.doi.org/10.3233/JAD-190475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971831/
https://www.ncbi.nlm.nih.gov/pubmed/31683476
http://dx.doi.org/10.3233/JAD-190475

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