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TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis

 Translocator protein 18 kDa (TSPO) is located in the mitochondrial outer membrane and plays an important role in steroidogenesis and cell survival. In the central nervous system (CNS), its expression is upregulated in neuropathologies such as Alzheimer’s disease (AD). Previously, we demonstrated th...

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Detalles Bibliográficos
Autores principales: Lejri, Imane, Grimm, Amandine, Hallé, François, Abarghaz, Mustapha, Klein, Christian, Maitre, Michel, Schmitt, Martine, Bourguignon, Jean-Jacques, Mensah-Nyagan, Ayikoe Guy, Bihel, Frederic, Eckert, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971832/
https://www.ncbi.nlm.nih.gov/pubmed/31256132
http://dx.doi.org/10.3233/JAD-190127