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Polygenic risk score for Alzheimer’s disease and trajectories of cardiometabolic risk factors in children

Introduction: Cardiometabolic factors are implicated in the aetiology of Alzheimer’s disease and may lie on the pathways linking genetic variants to Alzheimer’s disease across the life course. We examined whether polygenic risk scores (PRS) were associated with cardiometabolic health indicators thro...

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Detalles Bibliográficos
Autores principales: Korologou-Linden, Roxanna, O'Keeffe, Linda, Howe, Laura D., Davey-Smith, George, Jones, Hannah J., Anderson, Emma L., Stergiakouli, Evie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971849/
https://www.ncbi.nlm.nih.gov/pubmed/31984241
http://dx.doi.org/10.12688/wellcomeopenres.15359.1