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Production, purification and characterization of recombinant human R-spondin1 (RSPO1) protein stably expressed in human HEK293 cells

BACKGROUND: The R-Spondin proteins comprise a family of secreted proteins, known for their important roles in cell proliferation, differentiation and death, by inducing the Wnt pathway. Several studies have demonstrated the importance of RSPOs in regulation of a number of tissue-specific processes,...

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Detalles Bibliográficos
Autores principales: Levin, Gabriel, Koga, Bruna Andrade Aguiar, Belchior, Gustavo Gross, Carreira, Ana Claudia Oliveira, Sogayar, Mari Cleide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971977/
https://www.ncbi.nlm.nih.gov/pubmed/31959207
http://dx.doi.org/10.1186/s12896-020-0600-0