A potential new mechanism for pregnancy loss: considering the role of LINE-1 retrotransposons in early spontaneous miscarriage

LINE1 retrotransposons are mobile DNA elements that copy and paste themselves into new sites in the genome. To ensure their evolutionary success, heritable new LINE-1 insertions accumulate in cells that can transmit genetic information to the next generation (i.e., germ cells and embryonic stem cell...

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Detalles Bibliográficos
Autores principales: Lou, Chao, Goodier, John L., Qiang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971995/
https://www.ncbi.nlm.nih.gov/pubmed/31964400
http://dx.doi.org/10.1186/s12958-020-0564-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971995/
https://www.ncbi.nlm.nih.gov/pubmed/31964400
http://dx.doi.org/10.1186/s12958-020-0564-x

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