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Core transcriptional regulatory circuits in prion diseases

Complex diseases involve dynamic perturbations of pathophysiological processes during disease progression. Transcriptional programs underlying such perturbations are unknown in many diseases. Here, we present core transcriptional regulatory circuits underlying early and late perturbations in prion d...

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Detalles Bibliográficos
Autores principales: Kim, Taek-Kyun, Lee, Inyoul, Cho, Ji-Hoon, Canine, Brenda, Keller, Andrew, Price, Nathan D., Hwang, Daehee, Carlson, George, Hood, Leroy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972013/
https://www.ncbi.nlm.nih.gov/pubmed/31959236
http://dx.doi.org/10.1186/s13041-020-0551-3