Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model

Tuberculous meningitis (TBM) is the most devastating form of extrapulmonary Mycobacterium tuberculosis infection in humans. Severe inflammation and extensive tissue damage drive the morbidity and mortality of this manifestation of tuberculosis (TB). Antibiotic treatment is ineffective at curing TBM...

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Detalles Bibliográficos
Autores principales: Kumar, Ranjeet, Kolloli, Afsal, Singh, Pooja, Vinnard, Christopher, Kaplan, Gilla, Subbian, Selvakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972508/
https://www.ncbi.nlm.nih.gov/pubmed/32010638
http://dx.doi.org/10.3389/fcimb.2019.00450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972508/
https://www.ncbi.nlm.nih.gov/pubmed/32010638
http://dx.doi.org/10.3389/fcimb.2019.00450

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