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Effects of Maribavir on P‐Glycoprotein and CYP2D6 in Healthy Volunteers

Maribavir is an investigational drug being evaluated in transplant recipients with cytomegalovirus infection. To understand potential drug‐drug interactions, we examined the effects of multiple doses of maribavir on cytochrome P450 (CYP) 2D6 and P‐glycoprotein (P‐gp) activity using probe substrates...

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Detalles Bibliográficos
Autores principales: Song, Ivy H., Ilic, Katarina, Murphy, Joseph, Lasseter, Kenneth, Martin, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972521/
https://www.ncbi.nlm.nih.gov/pubmed/31385617
http://dx.doi.org/10.1002/jcph.1504