Auxiliary subunits control biophysical properties and response to compound NS5806 of the Kv4 potassium channel complex

Kv4 pore‐forming subunits co‐assemble with β‐subunits including KChIP2 and DPP6 and the resultant complexes conduct cardiac transient outward K(+) current (I (to)). Compound NS5806 has been shown to potentate I (to) in canine cardiomyocytes; however, its effects on I (to) in other species yet to be...

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Detalles Bibliográficos
Autores principales: Zhang, Hongxue, Zhang, Hua, Wang, Chanjuan, Wang, Yuhong, Zou, Ruya, Shi, Chenxia, Guan, Bingcai, Gamper, Nikita, Xu, Yanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972550/
https://www.ncbi.nlm.nih.gov/pubmed/31914636
http://dx.doi.org/10.1096/fj.201902010RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972550/
https://www.ncbi.nlm.nih.gov/pubmed/31914636
http://dx.doi.org/10.1096/fj.201902010RR

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