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Auxiliary subunits control biophysical properties and response to compound NS5806 of the Kv4 potassium channel complex
Kv4 pore‐forming subunits co‐assemble with β‐subunits including KChIP2 and DPP6 and the resultant complexes conduct cardiac transient outward K(+) current (I (to)). Compound NS5806 has been shown to potentate I (to) in canine cardiomyocytes; however, its effects on I (to) in other species yet to be...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972550/ https://www.ncbi.nlm.nih.gov/pubmed/31914636 http://dx.doi.org/10.1096/fj.201902010RR |