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Recovery of viable endocrine‐specific cells and transcriptomes from human pancreatic islet‐engrafted mice

Human pancreatic islets engrafted into immunodeficient mice serve as an important model for in vivo human diabetes studies. Following engraftment, islet function can be monitored in vivo by measuring circulating glucose and human insulin; however, it will be important to recover viable cells for mor...

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Detalles Bibliográficos
Autores principales: Redick, Sambra D., Leehy, Linda, Rittenhouse, Ann R., Blodgett, David M., Derr, Alan G., Kucukural, Alper, Garber, Manuel G., Shultz, Leonard D., Greiner, Dale L., Wang, Jennifer P., Harlan, David M., Bortell, Rita, Jurczyk, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972551/
https://www.ncbi.nlm.nih.gov/pubmed/31914605
http://dx.doi.org/10.1096/fj.201901022RR