Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus‐induced lung inflammation in mice

BACKGROUND AND OBJECTIVE: Influenza A viruses (IAV) cause respiratory tract infections that can be fatal when the virus spreads to the alveolar space (i.e. alveolitis), and this is mainly observed with highly pathogenic strains. Reactive oxygen species (ROS) production by the NOX2 NADPH oxidase in e...

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Detalles Bibliográficos
Autores principales: To, Eunice E., Luong, Raymond, Diao, Jiayin, O’ Leary, John J., Brooks, Doug A., Vlahos, Ross, Selemidis, Stavros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972593/
https://www.ncbi.nlm.nih.gov/pubmed/30884042
http://dx.doi.org/10.1111/resp.13524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972593/
https://www.ncbi.nlm.nih.gov/pubmed/30884042
http://dx.doi.org/10.1111/resp.13524

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