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l‐Fucose prevention of renal ischaemia/reperfusion injury in Mice

In a recent study, we identified a fucosylated damage‐associated ligand exposed by ischemia on renal tubule epithelial cells, which after recognition by collectin‐11 (CL‐11 or collectin kidney 1 (CL‐K1)), initiates complement activation and acute kidney injury. We exploited the ability to increase t...

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Detalles Bibliográficos
Autores principales: Howard, Mark C., Nauser, Christopher L., Farrar, Conrad A., Wallis, Russell, Sacks, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972607/
https://www.ncbi.nlm.nih.gov/pubmed/31914693
http://dx.doi.org/10.1096/fj.201901582R