A Photoactivatable Small‐Molecule Probe for the In Vivo Capture of Polyketide Intermediates

A photolabile carba(dethia) malonyl N‐acetylcysteamine derivative was devised and prepared for the trapping of biosynthetic polyketide intermediates following light activation. From the lasalocid A polyketide assembly in a mutant strain of the soil bacterium Streptomyces lasaliensis, a previously un...

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Detalles Bibliográficos
Autores principales: Kilgour, Samantha L., Jenkins, Robert, Tosin, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972646/
https://www.ncbi.nlm.nih.gov/pubmed/31617624
http://dx.doi.org/10.1002/chem.201903661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972646/
https://www.ncbi.nlm.nih.gov/pubmed/31617624
http://dx.doi.org/10.1002/chem.201903661

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