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Vitamin D differentially regulates colon stem cells in patient‐derived normal and tumor organoids

Intestine is a major target of vitamin D and several studies indicate an association between vitamin D deficiency and inflammatory bowel diseases (IBD), but also increased colorectal cancer (CRC) risk and mortality. However, the putative effects of 1α,25‐dihydroxyvitamin D(3) (calcitriol), the activ...

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Podrobná bibliografie
Hlavní autoři: Fernández‐Barral, Asunción, Costales‐Carrera, Alba, Buira, Sandra P., Jung, Peter, Ferrer‐Mayorga, Gemma, Larriba, María Jesús, Bustamante‐Madrid, Pilar, Domínguez, Orlando, Real, Francisco X., Guerra‐Pastrián, Laura, Lafarga, Miguel, García‐Olmo, Damián, Cantero, Ramón, Del Peso, Luis, Batlle, Eduard, Rojo, Federico, Muñoz, Alberto, Barbáchano, Antonio
Médium: Online Článek Text
Jazyk:English
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972655/
https://www.ncbi.nlm.nih.gov/pubmed/31306552
http://dx.doi.org/10.1111/febs.14998