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Vitamin D differentially regulates colon stem cells in patient‐derived normal and tumor organoids
Intestine is a major target of vitamin D and several studies indicate an association between vitamin D deficiency and inflammatory bowel diseases (IBD), but also increased colorectal cancer (CRC) risk and mortality. However, the putative effects of 1α,25‐dihydroxyvitamin D(3) (calcitriol), the activ...
Autores principales: | Fernández‐Barral, Asunción, Costales‐Carrera, Alba, Buira, Sandra P., Jung, Peter, Ferrer‐Mayorga, Gemma, Larriba, María Jesús, Bustamante‐Madrid, Pilar, Domínguez, Orlando, Real, Francisco X., Guerra‐Pastrián, Laura, Lafarga, Miguel, García‐Olmo, Damián, Cantero, Ramón, Del Peso, Luis, Batlle, Eduard, Rojo, Federico, Muñoz, Alberto, Barbáchano, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972655/ https://www.ncbi.nlm.nih.gov/pubmed/31306552 http://dx.doi.org/10.1111/febs.14998 |
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