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Kidney transplant monitoring by urinary flow cytometry: Biomarker combination of T cells, renal tubular epithelial cells, and podocalyxin-positive cells detects rejection

Creatinine and proteinuria are used to monitor kidney transplant patients. However, renal biopsies are needed to diagnose renal graft rejection. Here, we assessed whether the quantification of different urinary cells would allow non-invasive detection of rejection. Urinary cell numbers of CD4(+) and...

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Detalles Bibliográficos
Autores principales: Goerlich, Nina, Brand, Hannah Antonia, Langhans, Valerie, Tesch, Sebastian, Schachtner, Thomas, Koch, Benjamin, Paliege, Alexander, Schneider, Wolfgang, Grützkau, Andreas, Reinke, Petra, Enghard, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972704/
https://www.ncbi.nlm.nih.gov/pubmed/31964937
http://dx.doi.org/10.1038/s41598-020-57524-7