Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway

Cycling hypoxia (cyH), also called intermittent hypoxia, occurs in solid tumors and affects different cell types in the tumor microenvironment and in particular the tumor-associated macrophages (TAMs). As cyH and TAMs both favor tumor progression, we investigated whether cyH could drive the pro-tumo...

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Detalles Bibliográficos
Autores principales: Delprat, Victor, Tellier, Céline, Demazy, Catherine, Raes, Martine, Feron, Olivier, Michiels, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972721/
https://www.ncbi.nlm.nih.gov/pubmed/31964911
http://dx.doi.org/10.1038/s41598-020-57677-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972721/
https://www.ncbi.nlm.nih.gov/pubmed/31964911
http://dx.doi.org/10.1038/s41598-020-57677-5

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