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Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway
Cycling hypoxia (cyH), also called intermittent hypoxia, occurs in solid tumors and affects different cell types in the tumor microenvironment and in particular the tumor-associated macrophages (TAMs). As cyH and TAMs both favor tumor progression, we investigated whether cyH could drive the pro-tumo...
Autores principales: | Delprat, Victor, Tellier, Céline, Demazy, Catherine, Raes, Martine, Feron, Olivier, Michiels, Carine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972721/ https://www.ncbi.nlm.nih.gov/pubmed/31964911 http://dx.doi.org/10.1038/s41598-020-57677-5 |
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