CRL4-Cereblon complex in Thalidomide Embryopathy: a translational investigation

The Cereblon-CRL4 complex has been studied predominantly with regards to thalidomide treatment of multiple myeloma. Nevertheless, the role of Cereblon-CRL4 in Thalidomide Embryopathy (TE) is still not understood. Not all embryos exposed to thalidomide develop TE, hence here we evaluate the role of t...

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Detalles Bibliográficos
Autores principales: Kowalski, Thayne Woycinck, Gomes, Julia do Amaral, Garcia, Gabriela Barreto Caldas, Fraga, Lucas Rosa, Paixao-Cortes, Vanessa Rodrigues, Recamonde-Mendoza, Mariana, Sanseverino, Maria Teresa Vieira, Schuler-Faccini, Lavinia, Vianna, Fernanda Sales Luiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972723/
https://www.ncbi.nlm.nih.gov/pubmed/31964914
http://dx.doi.org/10.1038/s41598-020-57512-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972723/
https://www.ncbi.nlm.nih.gov/pubmed/31964914
http://dx.doi.org/10.1038/s41598-020-57512-x

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